Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene

Inducible nitric oxide synthase (iNOS), an enzyme that produces toxic amounts of nitric oxide, is expressed in a number of brain pathologies, including cerebral ischemia. We used mice with a null mutation of the iNOS gene to study the role of iNOS in ischemic brain damage. Focal cerebral ischemia wa...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Iadecola, Costantino, Zhang, Fangyi, Casey, Robyn, Nagayama, Masao, Ross, M. Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1997
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573582/
https://ncbi.nlm.nih.gov/pubmed/9364062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-23-09157.1997
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