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Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene

Inducible nitric oxide synthase (iNOS), an enzyme that produces toxic amounts of nitric oxide, is expressed in a number of brain pathologies, including cerebral ischemia. We used mice with a null mutation of the iNOS gene to study the role of iNOS in ischemic brain damage. Focal cerebral ischemia wa...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Iadecola, Costantino, Zhang, Fangyi, Casey, Robyn, Nagayama, Masao, Ross, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573582/
https://ncbi.nlm.nih.gov/pubmed/9364062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-23-09157.1997
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