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Secondary Activation of a Cation Conductance Is Responsible for NMDA Toxicity in Acutely Isolated Hippocampal Neurons

One of the key questions concerning glutamate toxicity is how a transient NMDA exposure can lead to a delayed death of neurons. To address this issue, we performed whole-cell recording on acutely isolated hippocampal CA1 neurons to monitor the membrane response after NMDA exposure. Transient NMDA ex...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Chen, Qiang X., Perkins, Katherine L., Choi, Dennis W., Wong, Robert K. S.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573521/
https://ncbi.nlm.nih.gov/pubmed/9151719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-11-04032.1997
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