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Sensitivity to Jerky Gene Dosage Underlies Epileptic Seizures in Mice

Animals with one deleted jerky allele are more susceptible to chemically induced seizures than wild-type mice and display recurrent behavioral seizures. The phenotype of these hemizygotes is characterized by no apparent neurological symptoms other than recurrent seizures reminiscent of human idiopat...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Donovan, Gerald P., Harden, Cynthia, Gal, Judit, Ho, Lap, Sibille, Etienne, Trifiletti, Rosario, Gudas, Lorraine J., Toth, Miklos
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573360/
https://ncbi.nlm.nih.gov/pubmed/9169517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-12-04562.1997
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