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The RNA Binding Domain of Jerky Consists of Tandemly Arranged Helix-Turn-Helix/Homeodomain-Like Motifs and Binds Specific Sets of mRNAs

A deficit in the Jerky protein in mice causes recurrent seizures reminiscent of temporal lobe epilepsy. Jerky is present in mRNA particles in neurons. We show that the N-terminal 168 amino acids of Jerky are necessary and sufficient for mRNA binding. The binding domain is similar to the two tandemly...

詳細記述

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書誌詳細
主要な著者: Liu, Wencheng, Seto, Jeremy, Sibille, Etienne, Toth, Miklos
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC156124/
https://ncbi.nlm.nih.gov/pubmed/12773553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.12.4083-4093.2003
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