Adenosine A(1) Receptor-Mediated Activation of Phospholipase C in Cultured Astrocytes Depends on the Level of Receptor Expression

Adenosine A(1) receptors induce an inhibition of adenylyl cyclase via G-proteins of the G(i/o) family. In addition, simultaneous stimulation of A(1) receptors and of receptor-mediated activation of phospholipase C (PLC) results in a synergistic potentiation of PLC activity. Evidence has accumulated...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Biber, Knut, Klotz, Karl-Norbert, Berger, Mathias, Gebicke-Härter, Peter J., van Calker, Dietrich
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573309/
https://ncbi.nlm.nih.gov/pubmed/9185533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-13-04956.1997
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