Amyloid β-Peptide Impairs Glucose Transport in Hippocampal and Cortical Neurons: Involvement of Membrane Lipid Peroxidation

A deficit in glucose uptake and a deposition of amyloid β-peptide (Aβ) each occur in vulnerable brain regions in Alzheimer’s disease (AD). It is not known whether mechanistic links exist between Aβ deposition and impaired glucose transport. We now report that Aβ impairs glucose transport in cultured...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Mark, Robert J., Pang, Zhen, Geddes, James W., Uchida, Koji, Mattson, Mark P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1997
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573165/
https://ncbi.nlm.nih.gov/pubmed/8994059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-03-01046.1997
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