Targeted Overexpression of the Neurite Growth-Associated Protein B-50/GAP-43 in Cerebellar Purkinje Cells Induces Sprouting after Axotomy But Not Axon Regeneration into Growth-Permissive Transplants

B-50/GAP-43 is a nervous tissue-specific protein, the expression of which is associated with axon growth and regeneration. Its overexpression in transgenic mice produces spontaneous axonal sprouting and enhances induced remodeling in several neuron populations (Aigner et al., 1995; Holtmaat et al.,...

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Publicado no:J Neurosci
Main Authors: Buffo, Annalisa, Holtmaat, Anthony J. D. G., Savio, Tiziana, Verbeek, J. Sjef, Oberdick, John, Oestreicher, A. Beate, Gispen, Wilhelm Hendrik, Verhaagen, Joost, Rossi, Ferdinando, Strata, Piergiorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573080/
https://ncbi.nlm.nih.gov/pubmed/9348347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-22-08778.1997
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