Targeted Overexpression of the Neurite Growth-Associated Protein B-50/GAP-43 in Cerebellar Purkinje Cells Induces Sprouting after Axotomy But Not Axon Regeneration into Growth-Permissive Transplants

B-50/GAP-43 is a nervous tissue-specific protein, the expression of which is associated with axon growth and regeneration. Its overexpression in transgenic mice produces spontaneous axonal sprouting and enhances induced remodeling in several neuron populations (Aigner et al., 1995; Holtmaat et al.,...

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Publié dans:J Neurosci
Auteurs principaux: Buffo, Annalisa, Holtmaat, Anthony J. D. G., Savio, Tiziana, Verbeek, J. Sjef, Oberdick, John, Oestreicher, A. Beate, Gispen, Wilhelm Hendrik, Verhaagen, Joost, Rossi, Ferdinando, Strata, Piergiorgio
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1997
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573080/
https://ncbi.nlm.nih.gov/pubmed/9348347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-22-08778.1997
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