In vivo single branch axotomy induces GAP-43–dependent sprouting and synaptic remodeling in cerebellar cortex

Plasticity in the central nervous system in response to injury is a complex process involving axonal remodeling regulated by specific molecular pathways. Here, we dissected the role of growth-associated protein 43 (GAP-43; also known as neuromodulin and B-50) in axonal structural plasticity by using...

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Autores principales: Allegra Mascaro, Anna Letizia, Cesare, Paolo, Sacconi, Leonardo, Grasselli, Giorgio, Mandolesi, Georgia, Maco, Bohumil, Knott, Graham W., Huang, Lieven, De Paola, Vincenzo, Strata, Piergiorgio, Pavone, Francesco S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696745/
https://ncbi.nlm.nih.gov/pubmed/23754371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219256110
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