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Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation
Transforming growth factor β is a disulfide-linked dimeric cytokine that occurs in three highly related isoforms (TGFβ1–TGFβ3) engaged in signaling functions through binding of cognate TGFβ receptors. To regulate this pathway, the cytokines are biosynthesized as inactive pro-TGFβs with an N-terminal...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6572864/ https://ncbi.nlm.nih.gov/pubmed/31209258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44943-4 |
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