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Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers

Chromatin of mammalian nucleus folds into discrete contact enriched regions such as Topologically Associating Domains (TADs). Folding hierarchy and internal organization of TADs is highly dynamic throughout cellular differentiation, and are correlated with gene activation and silencing. To account f...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shukron, O., Piras, V., Noordermeer, D., Holcman, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572804/
https://ncbi.nlm.nih.gov/pubmed/31201308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10402-x
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