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Transient chromatin properties revealed by polymer models and stochastic simulations constructed from Chromosomal Capture data

Chromatin organization can be probed by Chromosomal Capture (5C) data, from which the encounter probability (EP) between genomic sites is presented in a large matrix. This matrix is averaged over a large cell population, revealing diagonal blocks called Topological Associating Domains (TADs) that re...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Shukron, Ofir, Holcman, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393903/
https://ncbi.nlm.nih.gov/pubmed/28369076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005469
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