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The Characteristics of PD-L1 Inhibitors, from Peptides to Small Molecules
The programmed cell death ligand protein 1 (PD-L1) is a member of the B7 protein family and consists of 290 amino acid residues. The blockade of the PD-1/PD-L1 immune checkpoint pathway is effective in tumor treatment. Results: Two pharmacophore models were generated based on peptides and small mole...
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| Published in: | Molecules |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6572691/ https://ncbi.nlm.nih.gov/pubmed/31137573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24101940 |
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