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Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry
Inspired by the many reported successful applications of DNA-encoded chemical libraries in drug discovery projects with protein targets, we decided to apply this platform to nucleic acid targets. We used a 120-billion-compound set of 33 distinct DNA-encoded chemical libraries and affinity-mediated s...
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| Publicado en: | Molecules |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6572338/ https://ncbi.nlm.nih.gov/pubmed/31137911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24102026 |
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