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Crystal structure of the flavin-dependent thymidylate synthase Thy1 from Thermus thermophilus with an extra C-terminal domain

The thymidylate synthases ThyA and Thy1 are enzymes that catalyse the formation of thymidine monophosphate from 2′-deoxyuridine monophosphate. Thy1 (or ThyX) requires flavin for catalytic reactions, while ThyA does not. In the present study, the crystal structure of the flavin-dependent thymidylate...

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Bibliografische gegevens
Gepubliceerd in:Acta Crystallogr F Struct Biol Commun
Hoofdauteurs: Ogawa, Aoba, Sampei, Gen-ichi, Kawai, Gota
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6572101/
https://ncbi.nlm.nih.gov/pubmed/31204692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19007192
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