Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Intrinsically disordered proteins (IDPs) can form functional oligomers and in some cases, insoluble disease related aggregates. It is therefore vital to understand processes and mechanisms that control pathway distribution. Divalent cations including Zn(2+) can initiate IDP oligomerisation through t...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Cragnell, Carolina, Staby, Lasse, Lenton, Samuel, Kragelund, Birthe B., Skepö, Marie
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571702/
https://ncbi.nlm.nih.gov/pubmed/31052346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9050168
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