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Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Intrinsically disordered proteins (IDPs) can form functional oligomers and in some cases, insoluble disease related aggregates. It is therefore vital to understand processes and mechanisms that control pathway distribution. Divalent cations including Zn(2+) can initiate IDP oligomerisation through t...

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發表在:Biomolecules
Main Authors: Cragnell, Carolina, Staby, Lasse, Lenton, Samuel, Kragelund, Birthe B., Skepö, Marie
格式: Artigo
語言:Inglês
出版: MDPI 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571702/
https://ncbi.nlm.nih.gov/pubmed/31052346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9050168
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