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Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Intrinsically disordered proteins (IDPs) can form functional oligomers and in some cases, insoluble disease related aggregates. It is therefore vital to understand processes and mechanisms that control pathway distribution. Divalent cations including Zn(2+) can initiate IDP oligomerisation through t...

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Vydáno v:Biomolecules
Hlavní autoři: Cragnell, Carolina, Staby, Lasse, Lenton, Samuel, Kragelund, Birthe B., Skepö, Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571702/
https://ncbi.nlm.nih.gov/pubmed/31052346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9050168
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