Lanean...

Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus

CD40 is a costimulatory receptor on APCs that is critical for the induction and maintenance of humoral and cell-mediated immunity. Accordingly, CD40 and its ligand, CD40L, have long been considered targets for the treatment of autoimmune diseases. We developed a rat/mouse chimeric anti-mouse CD40 an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Perper, Stuart J., Westmoreland, Susan V., Karman, Jozsef, Twomey, Rachel, Seagal, Jane, Wang, Rui, McRae, Bradford L., Clarke, Stephen H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AAI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571503/
https://ncbi.nlm.nih.gov/pubmed/31109957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900043
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!