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A natural point mutation in the bitter taste receptor TAS2R16 causes inverse agonism of arbutin in lemur gustation

Bitter taste enables the detection of potentially harmful substances and is mediated by bitter taste receptors, TAS2Rs, in vertebrates. Few antagonists and inverse agonists of TAS2Rs have been identified, especially natural compounds. TAS2R16s in humans, apes and Old World monkeys (Catarrhini, Anthr...

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Detalles Bibliográficos
Publicado en:Proc Biol Sci
Main Authors: Itoigawa, Akihiro, Hayakawa, Takashi, Suzuki-Hashido, Nami, Imai, Hiroo
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571456/
https://ncbi.nlm.nih.gov/pubmed/31161904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2019.0884
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