A natural point mutation in the bitter taste receptor TAS2R16 causes inverse agonism of arbutin in lemur gustation

Bitter taste enables the detection of potentially harmful substances and is mediated by bitter taste receptors, TAS2Rs, in vertebrates. Few antagonists and inverse agonists of TAS2Rs have been identified, especially natural compounds. TAS2R16s in humans, apes and Old World monkeys (Catarrhini, Anthr...

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Vydáno v:Proc Biol Sci
Hlavní autoři: Itoigawa, Akihiro, Hayakawa, Takashi, Suzuki-Hashido, Nami, Imai, Hiroo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2019
Témata:
Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571456/
https://ncbi.nlm.nih.gov/pubmed/31161904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2019.0884
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