Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

During development, hematopoietic stem and progenitor cells (HSPCs) arise from specialized endothelial cells by a process termed endothelial-to-hematopoietic transition (EHT). The genetic program driving human HSPC emergence remains largely unknown. We previously reported that the generation of hemo...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Gomes, Andreia M., Kurochkin, Ilia, Chang, Betty, Daniel, Michael, Law, Kenneth, Satija, Namita, Lachmann, Alexander, Wang, Zichen, Ferreira, Lino, Ma’ayan, Avi, Chen, Benjamin K., Papatsenko, Dmitri, Lemischka, Ihor R., Moore, Kateri A., Pereira, Carlos-Filipe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571141/
https://ncbi.nlm.nih.gov/pubmed/30517869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.032
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