Induction of a Hemogenic Program in Mouse Fibroblasts

Definitive hematopoiesis emerges during embryogenesis via an endothelial-to-hematopoietic transition. We attempted to induce this process in mouse fibroblasts by screening a panel of factors for hemogenic activity. We identified a combination of four transcription factors, Gata2, Gfi1b, cFos, and Et...

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Autors principals: Pereira, Carlos-Filipe, Chang, Betty, Qiu, Jiajing, Niu, Xiaohong, Papatsenko, Dmitri, Hendry, Caroline E., Clark, Neil R., Nomura-Kitabayashi, Aya, Kovacic, Jason C., Ma’ayan, Avi, Schaniel, Christoph, Lemischka, Ihor R., Moore, Kateri
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735774/
https://ncbi.nlm.nih.gov/pubmed/23770078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.05.024
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