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Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges
Abnormal blood and lymphatic vessels create a hostile tumor microenvironment characterized by hypoxia, low pH, and elevated interstitial fluid pressure. These abnormalities fuel tumor progression, immunosuppression, and treatment resistance. In 2001, we proposed a novel hypothesis that the judicious...
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| Udgivet i: | Annu Rev Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6571025/ https://ncbi.nlm.nih.gov/pubmed/30742782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-020518-114700 |
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