A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma

Neurofibromatosis type II (NF2) is a disease that lacks effective therapies. NF2 is characterized by bilateral vestibular schwannomas (VSs) that cause progressive and debilitating hearing loss, leading to social isolation and increased rates of depression. A major limitation in NF2 basic and transla...

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Publicado no:Nat Protoc
Main Authors: Chen, Jie, Landegger, Lukas D., Sun, Yao, Ren, Jun, Maimon, Nir, Wu, Limeng, Ng, Mei R., Chen, John W., Zhang, Na, Zhao, Yingchao, Gao, Xing, Fujita, Takeshi, Roberge, Sylvie, Huang, Peigen, Jain, Rakesh K., Plotkin, Scott R, Stankovic, Konstantina M., Xu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571021/
https://ncbi.nlm.nih.gov/pubmed/30617350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0105-7
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