A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma

Neurofibromatosis type II (NF2) is a disease that lacks effective therapies. NF2 is characterized by bilateral vestibular schwannomas (VSs) that cause progressive and debilitating hearing loss, leading to social isolation and increased rates of depression. A major limitation in NF2 basic and transla...

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Veröffentlicht in:Nat Protoc
Hauptverfasser: Chen, Jie, Landegger, Lukas D., Sun, Yao, Ren, Jun, Maimon, Nir, Wu, Limeng, Ng, Mei R., Chen, John W., Zhang, Na, Zhao, Yingchao, Gao, Xing, Fujita, Takeshi, Roberge, Sylvie, Huang, Peigen, Jain, Rakesh K., Plotkin, Scott R, Stankovic, Konstantina M., Xu, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571021/
https://ncbi.nlm.nih.gov/pubmed/30617350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0105-7
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