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Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants
BACKGROUND: Extensive genome rearrangements, known as chromothripsis, have been recently identified in several cancer types. Chromothripsis leads to complex structural variants (cSVs) causing aberrant gene expression and the formation of de novo fusion genes, which can trigger cancer development, or...
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| 出版年: | PeerJ |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
PeerJ Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6571010/ https://ncbi.nlm.nih.gov/pubmed/31223530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7071 |
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