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Identification of TCR Vβ11-2-Dβ1-Jβ1-1 T cell clone specific for WT1 peptides using high-throughput TCRβ gene sequencing
We previously identified a TCR Vβ21 T cell clone which was specific to CML patients, and demonstrated that TCR Vα13/β21 gene-modified CD3(+) T cells had specific cytotoxicity for HLA-A11(+) K562 cells. However, it remains unclear which antigen is specifically recognized by the TCR Vβ21 T cell clone....
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| Publicado en: | Biomark Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6570921/ https://ncbi.nlm.nih.gov/pubmed/31223481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-019-0163-1 |
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