Signaling pathways involved in chronic myeloid leukemia pathogenesis: The importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells

OBJECTIVE(S): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to impo...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Moradi, Foruzan, Babashah, Sadegh, Sadeghizadeh, Majid, Jalili, Arsalan, Hajifathali, Abbas, Roshandel, Hajifathali
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2019
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570743/
https://ncbi.nlm.nih.gov/pubmed/31231484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.31879.7666
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