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CRISPR-Cas-Mediated Chemical Control of Transcriptional Dynamics in Yeast

Synthetic CRISPR-Cas transcription factors enable the construction of complex gene expression programs, and chemically-inducible systems allow precise control over the expression dynamics. To provide additional modes of regulatory control, we have constructed a chemically-inducible CRISPR activation...

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Publicat a:Chembiochem
Autors principals: Cunningham-Bryant, Daniel, Sun, Jingwen, Fernandez, Brianna, Zalatan, Jesse G.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570556/
https://ncbi.nlm.nih.gov/pubmed/30710419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800823
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