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Signed, Sealed, Delivered: Conjugate and Prodrug Strategies as Targeted Delivery Vectors for Antibiotics

Innate and developed resistance mechanisms of bacteria to antibiotics are obstacles in the design of novel drugs. However, antibacterial prodrugs and conjugates have shown promise in circumventing resistance and tolerance mechanisms via directed delivery of antibiotics to the site of infection or to...

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Vydáno v:ACS Infect Dis
Hlavní autoři: Cheng, Ana V., Wuest, William M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570538/
https://ncbi.nlm.nih.gov/pubmed/30969100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00019
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