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HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

Viral infection is usually studied at the population level by averaging over millions of cells. However, infection at the single-cell level is highly heterogeneous, with most infected cells giving rise to no or few viral progeny while some cells produce thousands. Analysis of Herpes Simplex virus 1...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Drayman, Nir, Patel, Parthiv, Vistain, Luke, Tay, Savaş
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570482/
https://ncbi.nlm.nih.gov/pubmed/31090537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46339
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