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Proteolytic processing of beta-amyloid precursor by calpain I

The beta-amyloid peptide is a core component of the neuritic plaques that accumulate in Alzheimer's disease. Since the beta-peptide resides within a family of precursor proteins (APPs), proteolytic processing of APP is required for beta-amyloid deposition into plaques. Here, we have examined th...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Siman, R, Card, JP, Davis, LG
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570374/
https://ncbi.nlm.nih.gov/pubmed/2115911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-07-02400.1990
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