Identification of MARPP-58, a morphine- and cyclic AMP-regulated phosphoprotein of 58 kDa, as tyrosine hydroxylase: evidence for regulation of its expression by chronic morphine in the rat locus coeruleus

Previously, we have identified a number of morphine- and cyclic AMP- regulated phosphoproteins (MARPPs) in the rat locus coeruleus (LC) and other brain regions. We now show that one of these phosphoproteins, a 58 kDa protein designated MARPP-58, is tyrosine hydroxylase. First, MARPP-58 comigrates wi...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Guitart, X, Hayward, M, Nisenbaum, LK, Beitner-Johnson, DB, Haycock, JW, Nestler, EJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1990
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570282/
https://ncbi.nlm.nih.gov/pubmed/1974920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-08-02649.1990
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