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Excitation of locus coeruleus neurons by vasoactive intestinal peptide: role of a cAMP and protein kinase A

In accord with previous studies, it was found that vasoactive intestinal peptide (VIP), a powerful activator of adenylate cyclase, and cAMP-active agents (i.e., 8-Br-cAMP, forskolin, and Ro20-1724) increased the firing rate of noradrenergic neurons in the locus coeruleus (LC) by inducing an inward c...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wang, YY, Aghajanian, GK
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570178/
https://ncbi.nlm.nih.gov/pubmed/2170595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-10-03335.1990
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