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Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures

To examine the roles of glycine in neurotoxicity caused by NMDA, primary rat cortical cultures were exposed to 100–300 microM NMDA plus glycine (0–3000 microM) or other glycine analogs in a simple saline solution, and toxicity was assessed by the amount of lactate dehydrogenase (LDH) released from t...

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Pubblicato in:J Neurosci
Autori principali: McNamara, D, Dingledine, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570035/
https://ncbi.nlm.nih.gov/pubmed/1980134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.10-12-03970.1990
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