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Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

The antagonist pharmacology of glutamate neurotoxicity was quantitatively examined in murine cortical cell cultures. Addition of 1- 3 mM DL-2-amino-5-phosphonovalerate (APV), or its active isomer D-APV, acutely to the exposure solution selectively blocked the neuroexcitation and neuronal cell select...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Choi, DW, Koh, JY, Peters, S
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569373/
https://ncbi.nlm.nih.gov/pubmed/2892896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.08-01-00185.1988
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