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HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

3-Amino-1-hydroxypyrrolid-2-one (HA-966) has been known for several years as an excitatory amino acid antagonist, acting principally at the N-methyl-D-aspartate (NMDA) receptor subtype. We report here that HA- 966 blocks NMDA responses through a selective interaction with the glycine modulatory site...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Foster, AC, Kemp, JA
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6569716/
https://ncbi.nlm.nih.gov/pubmed/2542488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.09-06-02191.1989
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