HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

Antzeko izenburuak

• 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex.
  nork: Kemp, J A, et al.
  Argitaratua: (1988)
• Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative.
  nork: Singh, L, et al.
  Argitaratua: (1990)
• Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor.
  nork: Henderson, G, et al.
  Argitaratua: (1990)
• N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands
  nork: Clausen, Rasmus P., et al.
  Argitaratua: (2008)
• d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor
  nork: Mothet, Jean-Pierre, et al.
  Argitaratua: (2000)