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Adenosine stimulates glycogenolysis in mouse cerebral cortex: a possible coupling mechanism between neuronal activity and energy metabolism

Adenosine promotes a concentration-dependent hydrolysis of 3H-glycogen newly synthesized from 3H-glucose by mouse cerebral cortical slices. The EC50 for this effect is 7 microM. Theophylline antagonizes the glycogenolysis induced by adenosine with an EC50 of 80 microM. The rank- order of potencies o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Magistretti, PJ, Hof, PR, Martin, JL
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568677/
https://ncbi.nlm.nih.gov/pubmed/3018195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.06-09-02558.1986
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