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DMPK gene DNA methylation levels are associated with muscular and respiratory profiles in DM1

OBJECTIVE: To assess the effects of dystrophia myotonica protein kinase (DMPK) DNA methylation (DNAme) epivariation on muscular and respiratory profiles in patients with myotonic dystrophy type 1 (DM1). METHODS: Phenotypes were assessed with standardized measures. Pyrosequencing of bisulfite-treated...

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Detalhes bibliográficos
Publicado no:Neurol Genet
Main Authors: Légaré, Cécilia, Overend, Gayle, Guay, Simon-Pierre, Monckton, Darren G., Mathieu, Jean, Gagnon, Cynthia, Bouchard, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568328/
https://ncbi.nlm.nih.gov/pubmed/31334355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000338
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