Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa

Hydroxyurea (HU) is clinically beneficial in sickle cell disease (SCD) through fetal hemoglobin (HbF) induction; however, the mechanism of HU is not yet fully elucidated. Selected miRNAs have been associated with HU-induced HbF production. We have investigated differential HU-induced global miRNA ex...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mnika, Khuthala, Mazandu, Gaston K., Jonas, Mario, Pule, Gift D., Chimusa, Emile R., Hanchard, Neil A., Wonkam, Ambroise
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568309/
https://ncbi.nlm.nih.gov/pubmed/31231425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00509
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