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Zn(OTf)(2)-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

Intramolecular hydroarylations of N-propargylated tetrahydrocarbolines were efficiently mediated using a unique combination of Zn(OTf)(2) with t-BuOH under neutral conditions. Use of the artificial force induced reaction method in the global reaction route mapping strategy provided insights into the...

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Vydáno v:Chem Sci
Hlavní autoři: Yorimoto, Sadaiwa, Tsubouchi, Akira, Mizoguchi, Haruki, Oikawa, Hideaki, Tsunekawa, Yoshiaki, Ichino, Tomoya, Maeda, Satoshi, Oguri, Hiroki
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568280/
https://ncbi.nlm.nih.gov/pubmed/31293753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01507h
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