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Development of an Alkaloid-Pyrone Annulation: Synthesis of Pleiomaltinine

ODD COUPLE: Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpam...

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Autors principals: Ziegler, Robert E., Tan, Shin-Jowl, Kam, Toh-Seok, Porco, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574645/
https://ncbi.nlm.nih.gov/pubmed/22893619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201204093
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