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The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition
The intestinal exporter MRP2 plays an important role in disposition and elimination of a wide range of drugs. Here, we aimed to clarify the impact of circadian clock on intestinal MRP2, and to determine the molecular mechanisms for generation of diurnal MRP2 expression. Methods: The regulatory effec...
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| Publié dans: | Theranostics |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ivyspring International Publisher
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6568180/ https://ncbi.nlm.nih.gov/pubmed/31244920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33395 |
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