Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma

The devastating prognosis of hepatocellular carcinoma (HCC) is partially attributed to chemotherapy resistance. Accumulating evidence suggests that the epithelial-mesenchymal transition (EMT) is a key driving force of carcinoma metastasis and chemoresistance in solid tumors. Leucine-rich repeat-cont...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Ma, Zhili, Guo, Deliang, Wang, Quanxiong, Liu, Pengpeng, Xiao, Yushao, Wu, Ping, Wang, Yitao, Chen, Baiyang, Liu, Zhisu, Liu, Quanyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568175/
https://ncbi.nlm.nih.gov/pubmed/31244936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30562
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