Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma

The devastating prognosis of hepatocellular carcinoma (HCC) is partially attributed to chemotherapy resistance. Accumulating evidence suggests that the epithelial-mesenchymal transition (EMT) is a key driving force of carcinoma metastasis and chemoresistance in solid tumors. Leucine-rich repeat-cont...

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Vydáno v:Theranostics
Hlavní autoři: Ma, Zhili, Guo, Deliang, Wang, Quanxiong, Liu, Pengpeng, Xiao, Yushao, Wu, Ping, Wang, Yitao, Chen, Baiyang, Liu, Zhisu, Liu, Quanyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568175/
https://ncbi.nlm.nih.gov/pubmed/31244936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30562
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