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M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124

Rationale: Microglia play a critical role in modulating cell death and neurobehavioral recovery in response to brain injury either by direct cell-cell interaction or indirect secretion of trophic factors. Exosomes secreted from cells are well documented to deliver bioactive molecules to recipient ce...

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Bibliographic Details
Published in:Theranostics
Main Authors: Song, Yaying, Li, Zongwei, He, Tingting, Qu, Meijie, Jiang, Lu, Li, Wanlu, Shi, Xiaojing, Pan, Jiaji, Zhang, Linyuan, Wang, Yongting, Zhang, Zhijun, Tang, Yaohui, Yang, Guo-Yuan
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568171/
https://ncbi.nlm.nih.gov/pubmed/31244932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30879
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