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Combination of CTLA-4 and PD-1 blockers for treatment of cancer

Targeting checkpoints of immune cell activation has been demonstrated to be the most effective approach for activation of anti-tumor immune responses. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1), both inhibitory checkpoints commonly seen on activat...

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Detaylı Bibliyografya
Yayımlandı:J Exp Clin Cancer Res
Yazar: Rotte, Anand
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567914/
https://ncbi.nlm.nih.gov/pubmed/31196207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1259-z
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