PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23

STAT3 plays very important roles in the initiation and development of tumors. Despite of extensive studies in repressing its activation and function via multiple ways, so far, there are few effective therapeutic methods to inhibit STAT3 in the clinic. STAT3 has two isoforms generated by alternative...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Wang, Xiaole, Guo, Jihua, Che, Xiaoxuan, Jia, Rong
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567812/
https://ncbi.nlm.nih.gov/pubmed/31223278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.33103
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