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PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23

STAT3 plays very important roles in the initiation and development of tumors. Despite of extensive studies in repressing its activation and function via multiple ways, so far, there are few effective therapeutic methods to inhibit STAT3 in the clinic. STAT3 has two isoforms generated by alternative...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Biol Sci
Päätekijät: Wang, Xiaole, Guo, Jihua, Che, Xiaoxuan, Jia, Rong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567812/
https://ncbi.nlm.nih.gov/pubmed/31223278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.33103
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