PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23

STAT3 plays very important roles in the initiation and development of tumors. Despite of extensive studies in repressing its activation and function via multiple ways, so far, there are few effective therapeutic methods to inhibit STAT3 in the clinic. STAT3 has two isoforms generated by alternative...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Int J Biol Sci
Huvudupphovsmän: Wang, Xiaole, Guo, Jihua, Che, Xiaoxuan, Jia, Rong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567812/
https://ncbi.nlm.nih.gov/pubmed/31223278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.33103
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk