Impact of Periprosthetic Fibroblast-Like Cells on Osteoclastogenesis in Co-Culture with Peripheral Blood Mononuclear Cells Varies Depending on Culture System

Co-culture studies investigating the role of periprosthetic fibroblasts (PPFs) in inflammatory osteoclastogenesis reveal contrary results, partly showing an osteoprotective function of fibroblasts and high OPG expression in monolayer. These data disagree with molecular analyses of original periosteo...

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Udgivet i:Int J Mol Sci
Main Authors: Koehler, Miriam I., Hartmann, Eliza S., Schluessel, Sabine, Beck, Felicitas, Redeker, Julia I., Schmitt, Baerbel, Unger, Marina, van Griensven, Martijn, Summer, Burkhard, Fottner, Andreas, Mayer-Wagner, Susanne
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567687/
https://ncbi.nlm.nih.gov/pubmed/31130703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102583
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