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B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors
BACKGROUND: PD-1 inhibitors are approved for multiple malignancies and function by stimulating T cells. However, the role of B cells in the anti-tumor activity of these drugs is unknown, as is their activity in patients who have received B cell depleting drugs or with immunoglobulin deficiencies. ME...
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| Publicado no: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6567557/ https://ncbi.nlm.nih.gov/pubmed/31200747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0613-1 |
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